Evaluate compound effect on inhibition of human liver CYP3A4, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1

Evaluate effect of compound on CYP450 isoenzyme activity in vitro - choose one isoenzyme from 1A2, 3A4, 2C9, 2C19 or 2D6

Determination of the CYP enzymes that are involved in the metabolism of a compound

Evaluate effect of compound in an in vitro CYP450 assay - choose one isoform: 1A2, 2C9, 2C19, 2D6 or 3A4

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Assess the potential for compounds to inhibit metabolism by CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6 or CYP3A4

Profiling of small molecules against a range of recombinant human CYP450 isozymes (including 3A4, 2D6, 2C9 and 2E1) in microsomes from insect cells infected with Baculovirus

Evaluation of the CYP450 inhibitory potential of test compounds using human liver microsomes

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Uses a cell reporter to measure the functional activation of hAhR in hepatic base cells

Uses a cell reporter to measure the functional activation of human PXR in hepatic base cells

Reporter assay to measure the functional activation of rat PXR in a rat hepatoma cell line

Uses a cell reporter to measure the functional activation of primate PXR in hepatic base cells

Uses a cell reporter to measure the functional activation of human PXR in hepatic base cells

Uses a cell reporter to measure the functional activation of human AhR in hepatic base cells